2/25/2024 0 Comments Nocturnal bowel movementsSleep restores people physically and psychologically. Sleep is a state characterized by changes in the level of consciousness, unresponsiveness to the surrounding environment, and inactivity of voluntary muscles. This article will discuss the relationship between sleep and various gastrointestinal illnesses, including gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colorectal cancer, and liver disease. Conversely, many gastrointestinal diseases affect the sleep-wake cycle and lead to poor sleep. Poor sleep has been shown to result in the exacerbation of gastrointestinal symptoms. There is a unique interplay between certain gastrointestinal diseases and sleep. 3 - 6 Although it is evident that sleep disturbances are often found in patients with gastrointestinal disease, it is difficult to determine the cause and effect of the disturbances. Recent studies have suggested a strong association between sleep disturbances and gastrointestinal diseases. 1 More importantly, long-term sleep deprivation has been found to increase overall morbidity and mortality. The cumulative long-term effects of sleep deprivation have been linked to an increased risk of a wide array of comorbidities, including hypertension, diabetes, obesity, stroke, and heart attack. 2 Most studies suggest that the daily sleep requirement for adults is 7 to 9 hours per night. 2 Sleep disorders have been linked to neurocognitive effects such as slower response time, impaired attention, and increased likelihood of falling asleep at work. 1 Patients with sleep deprivation experience a reduction in productivity and quality of life along with an increase in accidents and errors in the workplace. Sleep disorders are estimated to affect 50 to 70 million Americans. There has been a recent surge of research evaluating sleep disturbances and their effect on overall health. This article reviews the current research on the interplay between sleep disorders, immune function, and gastrointestinal diseases. It is important for gastroenterologists to be aware of the relationship between sleep disorders and gastrointestinal illnesses to ensure good care for patients. Alterations in these cytokines have been seen in certain gastrointestinal diseases, such as gastroesophageal reflux disease, inflammatory bowel disease, liver disorders, and colorectal cancer. Proinflammatory cytokines, such as tumor necrosis factor, interleukin-1, and interleukin-6, have been associated with sleep dysfunction. Recent studies have suggested that there is a strong association between sleep disturbances and gastrointestinal diseases. Many patients experience sleep disturbances, which can increase the risk of medical conditions such as hypertension, obesity, stroke, and heart disease as well as increase overall mortality. Sleep deprivation and impaired sleep quality have been associated with poor health outcomes.
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